Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Application of C8H11BO4.
Robinson, Alan;Dieckmann, Michael;Krieger, Jean-Philippe;Vent-Schmidt, Thomas;Marantelli, Dominique;Kohlbrenner, Ralf;Gribkov, Denis;Simon, Levente L.;Austrup, David;Rod, Alexandre;Bochet, Christian G. research published 《 Development and Scale-Up of a Novel Photochemical C-N Oxidative Coupling》, the research content is summarized as follows. A visible light promoted C-N-coupling of a functionalized pyridazinone with veratrole was developed to forge the central C-N bond of an agrochem. intermediate. Dosing aqueous NaOCl and 4% O2 in N2 under blue light irradiation (460 nm) was key to promote the desired transformation while generating benign wastes. Mechanistic studies suggest the formation of a N-chloro species that undergoes selective coupling via a radical pathway induced by the combination of light and oxygen. Further development led to an optimized semi-batch process, which was successfully scaled up to an initial 20 L and then 1.2 m3.
122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., Application of C8H11BO4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem