Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 122775-35-3, formula is C8H11BO4, Name is 3,4-Dimethoxyphenylboronic acid. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. COA of Formula: C8H11BO4.
Manjappa, Kiran B.;Jhang, Jia-Wei;Lakshmi, K. C. Seetha;Yang, Ding-Yah research published 《 Four-Component Construction of Coumarin-Fused Pyrrolo[2,1-a]isoquinoline: Expedient Synthesis of Lamellarins and Their Regioselective Demethylation》, the research content is summarized as follows. Construction of the coumarin-fused pyrrolo[2,1-a]isolquinoline skeletons I (R = H, Me; R1 = H, OMe; R2 = H, OMe; R3 = H, OMe, Cl, diethylaminyl; R4 = H, Me; R5 = H; R4R5 = -(CH=CH-CH=CH)-; R6 = H) was realized through a four-component reaction between isoquinolines II, Et bromoacetate, o-hydroxybenzaldehydes 2-OH-4-R3-5-R4-6-R5C6HCHO and nitromethane. This methodol. was further extended to the synthesis of lamellarin D tri-Me ether I (R = H; R1 = R2 = R3 = R4 = OMe; R5 = H; R6 = 3,4-dimethoxyphenyl) and a formal synthesis of lamellarin D. The controlled demethylation of lamellarin D tri-Me ether yielded dihydroxy and tetrahydroxy lamellarin analogs I (R = H; R1 = R2 = OMe; R3 = OH, OMe; R4 = OH, OMe; R5 = H; R6 = 3,4-dihydroxyphenyl, 3,4-dimethoxyphenyl) regioselectively.
122775-35-3, 3,4-Dimethoxyphenylboronic acid is a useful research compound. Its molecular formula is C8H11BO4 and its molecular weight is 181.98 g/mol. The purity is usually 95%.
3,4-Dimethoxyphenylboronic acid contains varying amounts of anhydride.
3,4-Dimethoxyphenylboronic acid is a bacterial mutagen. A useful intermediate for organic synthesis.
3,4-Dimethoxyphenylboronic acid is a boronate ester that has been shown to be an effective coupling partner for the Suzuki reaction. It has also been used in cancer therapy and as a photochemical probe for the study of biological properties. 3,4-Dimethoxyphenylboronic acid has been shown to demethylate DNA and inhibit methionine aminopeptidase activity. It also cross-couples with halides, such as chlorides or iodides, and activates tertiary alcohols. 3,4-Dimethoxyphenylboronic acid is soluble in organic solvents and can be used in supramolecular chemistry., COA of Formula: C8H11BO4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem