On May 31, 2022, Yerien, Damian E.; Barata-Vallejo, Sebastian; Mansilla, Daniela; Postigo, Al published an article.COA of Formula: C8H10O2 The title of the article was Rose Bengal-photocatalyzed perfluorohexylation reactions of organic substrates in water. Applications to late-stage syntheses. And the article contained the following:
Rose Bengal-photocatalyzed perfluorohexylation of olefins, alkynes and electron-rich aromatic compounds in water was achieved employing perfluorohexyl iodide as fluoroalkyl source and TMEDA as sacrificial donor under green LED irradn to afford perfluoro compounds R1CHICH2C6F13 [R1 = CH2OPh, CHOH(CH2)5], R2HC=CHC6F13 [R2 = Ph, n-pentyl, (D)-(-)Norgestreyl] and I [R3 = 4-Me, 4-NO2, 2,6-(Me)2, etc.; R4 = OMe, NH2]. Alkenes and alkynes rendered products derived from the atom transfer radical addition (ATRA) pathway, and in the case of alkynes, exclusively as E-stereoisomers. These were the first examples of photocatalyzed ATRA reactions carried out excursively in water alone. The reactions of aromatic compounds under the current protocol in water present the advantage of employing a perfluoroalkyl iodide (C6F13-I) as source of perfluorohexyl radicals. Examples of photocatalytic late-stage incorporations of fluoroalkyl moieties into two com. drugs of widespread used were reported. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).COA of Formula: C8H10O2
The Article related to perfluoro compound green preparation, alkene perfluorohexylation rose bengal photocatalyst, alkyne perfluorohexylation rose bengal photocatalyst, aromatic compound perfluorohexylation rose bengal photocatalyst, late-stage perfluoroalkylation, perfluoroalkylation of alkynes, perfluoroalkylation of arenes, perfluoroalkylation of olefins, photocatalysis in water and other aspects.COA of Formula: C8H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem