On September 9, 2022, Xu, Ren-Rui; Bao, Xuanzhang; Huo, Yong-Wang; Miao, Ren-Guan; Wen, Dan; Dai, Weiqi; Qi, Xinxin; Wu, Xiao-Feng published an article.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline The title of the article was Palladium-Catalyzed Domino Carbopalladation/Carbonylative Cyclization: Synthesis of Heterocycles bearing Oxindoles and 3-Acylbenzofuran/3-Acylindole Moieties. And the article contained the following:
A novel and straightforward methodol. for palladium-catalyzed carbopalladation-initiated domino carbonylative cyclization to construct bisheterocycles was established. With TFBen as an efficient and convenient CO source, the protocol wass capable of generating oxindole and 3-acylbenzofuran/3-acylindole moieties from the corresponding N-(o-iodoaryl)acrylamides and o-alkynylphenols/o-alkynylanilines with the formation of three C-C bonds and one C-O/C-N bond in a single one-step operation. A wide range of bisheterocycles bearing oxindoles and 3-acylbenzofurans/3-acylindoles were prepared in moderate to excellent yields with good functional group tolerance. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline
The Article related to iodophenyl acrylamide ethynylphenol tfben palladium tandem carbonylative heterocyclization, benzofuranyl oxindolyl ethanone preparation, ethynylaniline iodoaryl acrylamide tfben palladium tandem carbonylative heterocyclization, oxindolyl indolylethanone preparation and other aspects.Application In Synthesis of 2-((4-Methoxyphenyl)ethynyl)aniline
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