On May 11, 2020, Gevorgyan, Ashot; Hopmann, Kathrin H.; Bayer, Annette published an article.Reference of 1,2-Dimethoxybenzene The title of the article was Formal C-H Carboxylation of Unactivated Arenes. And the article contained the following:
A formal C-H carboxylation of unactivated arenes e.g., I using CO2 in green solvents is described. The present strategy combines a sterically controlled Ir-catalyzed C-H borylation followed by a Cu-catalyzed carboxylation of the in situ generated organoboronates. The reaction is highly regioselective for the C-H carboxylation of unactivated arenes e.g., I (1,3-disubstituted and 1,2,3-trisubstituted benzenes, 1,2- or 1,4-sym. substituted benzenes, fluorinated benzenes and different heterocycles). The developed methodol. was applied to the late-stage C-H carboxylation of com. drugs and ligands. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Reference of 1,2-Dimethoxybenzene
The Article related to carboxyl unactivated arene preparation green chem regioselective, unactivated arene carbon dioxide carboxylation copper catalyst, carbon dioxide aryl boronate carboxylation copper catalyst, c−h activation, carbon dioxide, carboxylation, green solvent, late-stage functionalization and other aspects.Reference of 1,2-Dimethoxybenzene
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