Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 530-59-6, formula is C11H12O5, Name is 3,5-Dimethoxy-4-hydroxycinnamic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Reference of 530-59-6.
Liu, Wenxiu;Ding, Lin;Xu, Jiawen;Shang, Yazhuo;Wang, Zejian;Liu, Honglai research published ã?Synthesis of sinapic acid modified sodium hyaluronate particles and the one-step processing of multiple Pickering emulsionã? the research content is summarized as follows. In this study, a series of sodium hyaluronate (HA) polymer mols. grafted with different amounts of sinapic acid (SA) groups were synthesized by adjusting the esterification reaction time, and the introduction of SA endows the polymer with both amphipathy and UV absorbability. The amphipathic polymer mols. (HA-SA) tend to self-assemble into polydisperse colloid particles and the particle properties of HA-SA, such as particle size, zeta potential as well as the interfacial activity were studied in detail. The results indicate that the properties of HA-SA particles prepared with different esterification reaction time are quite different due to the different graft amounts of SA. The graft amount of SA increased with the prolongation of esterification reaction time, and the interfacial activity of the obtained HA-SA particles also increased gradually, but an excessively high graft amount would make the polymer too hydrophobic and thus lead to the interfacial activity reduce slightly. By controlling the esterification reaction time within an appropriate range, the prepared particles show significant interfacial activity and are apt to linger on the interface of oil-water to reduce the interfacial tension, which has potential to be a new promising stabilizer of emulsions. Further studies show that, benefiting from the polydispersity of the HA-SA particles, the water-in-oil-in-water (W/O/W) multiple Pickering emulsion can be prepared by one-step homogenization using HA-SA particles as stabilizer.
Reference of 530-59-6, Sinapinic acid is a chemical compound that is the dihydroxybenzoic acid derivative of sinapic acid. It has been shown to have anti-inflammatory properties in vitro and in vivo. Sinapinic acid inhibits the activity of various enzymes, such as cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase-activating protein (FLAP). It also decreases levels of adhesion molecules and downregulates inflammatory response genes. Sinapinic acid has been shown to reduce inflammation by inhibiting the formation of proinflammatory mediators, such as prostaglandin E2 or leukotriene B4, in endothelial cells and mammary epithelial cells.
Sinapic acid is a phenylpropanoid hydroxycinnamic acid with diverse biological activities. Sinapic acid inhibits collagen-induced human platelet aggregation by up to 70% in vitro (IC50 = 1.03 mM). It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) free radicals with IC50 values of 8.3 and 5.4 μg/ml, respectively. Sinapic acid (200 μM) reduces colony formation of SW480 human colon carcinoma cells by 4-fold. It also inhibits colony formation of E. coli, S. enteritidis, and S. aureus on agar (MICs = 2.2, 2, and 1.8 mM, respectively). In vivo, sinapic acid (4 mg/kg, p.o.) increases the time spent in the open arms of the elevated plus maze by approximately 15% in mice, an effect that can be blocked by the GABAA receptor antagonists flumazenil and bicuculline. Sinapic acid is also commonly used as a matrix in protein mass spectrometry.
Sinapic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
cis-Sinapic acid, also known as cis-sinapate or synapitic acid, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. cis-Sinapic acid is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, cis-sinapic acid is primarily located in the cytoplasm. Outside of the human body, cis-sinapic acid can be found in common pea and pulses. This makes cis-sinapic acid a potential biomarker for the consumption of these food products.
Cis-sinapic acid is a 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid in which the double bond has cis-configuration. It has been isolated from the shoots of alfalfa. It has a role as a plant metabolite., 530-59-6.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem