Ethers are a class of organic compounds that contain an ether groupâan oxygen atom connected to two alkyl or aryl groups. 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether.They have the general formula RâOâRâ? where R and Râ?represent the alkyl or aryl groups. Related Products of 111-90-0.
Lee, Seon-Kwang;Ha, Eun-Sol;Jeong, Ji-Su;Kim, Sebin;Park, Heejun;Kim, Jeong-Soo;Yoo, Jin-Wook;Moon, Hyung Ryong;Jung, Yunjin;Kim, Min-Soo research published ã?Determination and correlation of solubility of efinaconazole in fifteen mono solvents and three binary mixed solvents at various temperaturesã? the research content is summarized as follows. In this study, the solubility data of the solid-liquid equilibrium of efinaconazole in acetone, acetonitrile, 1-butanol, diethylene glycol monoethyl ether (DEGME), dichloromethane, DMF (DMF), ethanol, Et acetate, methanol, 1-propanol, 2-propanol, propylene glycol, polyethylene glycol 400 (PEG 400), THF, water, and three binary mixed solvents (DEGME + water, ethanol + water, and PEG 400 + water) were measured at five different temperatures (288.15-308.15 K) using the shake-flask technique. The solubility of efinaconazole in the fifteen mono solvents was highest in dichloromethane, followed by THF, DMF, and acetone, and lowest in water. In the binary mixtures, the solubility of efinaconazole increased with an increase in the DEGME, ethanol, and PEG 400 mass fraction at a defined temperature, resp. According to the Kamlet-Taft linear solvation energy relationship model anal., the self-cohesiveness of the solvent indicating solvent-solvent interaction was the main factor affecting the solubility of efinaconazole, which resulted in decreased solubility Nine models, including the van’t Hoff, modified Apelblat, Buchowski-Ksiazczak λh, simplified CNIBS/R-K, Jouyban-Acree, Jouyban-Acree-van’t Hoff, Jouyban-Acree-modified Apelblat, Sun, and Ma models, were used to regress the exptl. solubility data of efinaconazole in fifteen mono solvents and the three binary mixtures In addition, the dissolution thermodn. properties of efinaconazole were estimated using a modified van’t Hoff anal. The exptl. solubility data and correlated models of efinaconazole in fifteen mono solvents and the three binary mixed solvents could be useful for the crystallization, purification, and development of liquid dosage forms such as topical solutions during drug development.
111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Related Products of 111-90-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem