Ethers do have nonbonding electron pairs on their oxygen atoms, 73724-45-5, formula is C18H17NO5, Name is Fmoc-Ser-OH. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Related Products of 73724-45-5.
Kim, Dong-in;Han, Seong-jae;Lim, Yong-beom research published ã?Unique behavior of the α-helix in bending deformationã? the research content is summarized as follows. The maximum degree of bending that can be tolerated by the rigid rod-like α-helix remains unknown; however, it should be very difficult or even impossible to make α-helixes with varying degrees of curvature in folded proteins. As an exptl. tractable model, here we utilize cyclic proteins and peptides to determine the maximum possible bending in the α-helix. We artificially enforced bending in the α-helixes by using variously sized macrocycles and compared the structural characteristics of the macrocycles with those of their linear counterparts. This differential anal. reveals that the radius of curvature (RC) for the maximally bent α-helix is approx. 10 times smaller than those of typical α-helixes found in natural proteins. Together with the novel finding of the limit of α-helix deformation, excessively bent α-helixes can be further utilized in designing de novo peptides and proteins with unique structures and peculiar functions.
Related Products of 73724-45-5, Fmoc-Ser-OH, also known as Fmoc-Ser-OH, is a useful research compound. Its molecular formula is C18H17NO5 and its molecular weight is 327.3 g/mol. The purity is usually 95%.
Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group., 73724-45-5.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem