《Synthesis of oxygen-heterocycles having linker components for trapping cysteine derivatives》 was written by Yoshioka, Eito; Minato, Ikko; Takashima, Hideki; Miyabe, Hideto. Computed Properties of C9H19NO4 And the article was included in Heterocycles in 2020. The article conveys some information:
Tricyclic oxygen-heterocycles having a linker component were synthesized for the site-specific modification of proteins and peptides. The linker components were initially introduced by Sonogashira-Hagihara cross coupling of 5-bromo-2-hydroxybenzaldehyde and a variety of alkynes. Next, the desired oxygen-heterocycles were synthesized by the condensation reaction of coupling products with cyclohexane-1,3-dione in the presence of N,N-diisopropylethylamine. Finally, the trapping ability of these oxygen-heterocycles was demonstrated by the representative reaction of 7-(3-(benzyloxy)prop-1-yn-1-yl)-4a-hydroxy-2,3,4,4a-tetrahydro-1H-xanthen-1-one with glutathione as a nucleophile having a thiol group. In the experiment, the researchers used many compounds, for example, tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6Computed Properties of C9H19NO4)
tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate(cas: 139115-91-6) belongs to ethers.Computed Properties of C9H19NO4Although ethers resist hydrolysis, they are cleaved by hydrobromic acid and hydroiodic acid. Hydrogen chloride cleaves ethers only slowly.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem