Recommanded Product: 2-Hydroxy-4-methoxybenzaldehydeIn 2021 ,《A ratiometric photoelectrochemical microsensor based on a small-molecule organic semiconductor for reliable in vivo analysis》 was published in Chemical Science. The article was written by Xiang, Yunhui; Kong, Yao; Feng, Wenqi; Ye, Xiaoxue; Liu, Zhihong. The article contains the following contents:
Photoelectrochem. (PEC) sensing has been developing quickly in recent years, while its in vivo application is still in the infancy. The complexity of biol. environments poses a high challenge to the specificity and reliability of PEC sensing. We herein proposed the concept of small-mol. organic semiconductor (SMOS)-based ratiometric PEC sensing making use of the structural flexibility as well as readily tunable energy band of SMOS. Xanthene skeleton-based CyOH was prepared as a photoactive mol., and its absorption band and corresponding PEC output can be modulated by an intramol. charge transfer process. As such, the target mediated shift of absorption offered the opportunity to construct a ratiometric PEC sensor. A proof-of-concept probe CyOThiols was synthesized and assembled on a Ti wire electrode (TiWE) to prepare a highly selective microsensor for thiols. Under two monochromatic laser excitation (808 nm and 750 nm), CyOThiols/TiWE offered a ratiometric signal (j808/j750), which exhibited pronounced capacity to offset the disturbance of environmental factors, guaranteeing its reliability for application in vivo. The ratiometric PEC sensor achieved the observation of bio-thiol release induced by cytotoxic edema and fluctuations of thiols in drug-induced epilepsy in living rat brains. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 2-Hydroxy-4-methoxybenzaldehyde)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Recommanded Product: 2-Hydroxy-4-methoxybenzaldehyde
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem