In 2019,Organic Letters included an article by Molloy, John J.; O’Rourke, Kerry M.; Frias, Carolina P.; Sloan, Nikki L.; West, Matthew J.; Pimlott, Sally L.; Sutherland, Andrew; Watson, Allan J. B.. Formula: C7H7IO. The article was titled 《Mechanism of Cu-Catalyzed Aryl Boronic Acid Halodeboronation Using Electrophilic Halogen: Development of a Base-Catalyzed Iododeboronation for Radiolabeling Applications》. The information in the text is summarized as follows:
An investigation into the mechanism of Cu-catalyzed aryl boronic acid halodeboronation using electrophilic halogen reagents is reported. Evidence is provided to show that this takes place via a boronate-driven ipso-substitution pathway and that Cu is not required for these processes to operate: general Lewis base catalysis is operational. This in turn allows the rational development of a general, simple, and effective base-catalyzed halodeboronation that is amenable to the preparation of 125I-labeled products for SPECT applications. In the experiment, the researchers used 1-Iodo-2-methoxybenzene(cas: 529-28-2Formula: C7H7IO)
1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Formula: C7H7IO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem