《Investigation of DNA binding and bioactivities of thioether containing Schiff base Copper(II), Cobalt(II) and Palladium(II) complexes: Synthesis, characterization, spectrochemical study, viscosity measurement》 was written by Maiti, Subir Kr; Kalita, Mukul; Singh, Anmol; Deka, Jahnabi; Barman, Pranjit. Recommanded Product: 673-22-3This research focused ontransition metal Schiff salicylaldehyde benzylthioaniline complex preparation bactericide; DNA binding transition metal Schiff salicylaldehyde benzylthioaniline complex; crystal structure transition metal salicylaldehyde benzylthioaniline complex. The article conveys some information:
Three complexes of an ONS donor ligand of the Schiff base [C21H19NO2S] (HL), [Cu(C21H18NO2S)2] (1) [Co(C21H18NO2S)2] (2) and [Pd(C21H18NO2SCl)] (3), were synthesized and characterized by elemental anal., FT-IR, 1H NMR, UV-Visible spectroscopy and single-crystal X-ray diffraction anal. Single crystal X-ray diffraction anal. reveals that the copper complex acquires a distorted pyramidal structure and the palladium complex acquires a square planar structure. All the compounds are stable at room temperature and they show very good antibacterial activities against gram-pos. and gram-neg. bacteria. DNA binding activities of the ligand and its Cu(II), Pd(II) and Co(II) complexes with CT-DNA were carried out in DMF and tris-buffer (5 mM, pH 7.3) solution; all the three complexes along with the ligand show a very good intercalative mode of DNA interaction with Kb values of 1.56(±0.03) x 105 for 1 and 1.02(±0.09) x 105 for 3. The DNA binding activity was confirmed by a hydrodynamic study (viscosity). The order of DNA binding activity is 1 > 3 > 2.2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 673-22-3) was used in this study.
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Recommanded Product: 673-22-3
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