《Phosphine-Mediated MBH-Type/Umpolung Addition Domino Sequence: Divergent Construction of Coumarins》 was published in Organic Letters in 2020. These research results belong to Deng, Zhi-Xiong; Zheng, Yu; Xie, Zhen-Zhen; Gao, Yue-Heng; Xiao, Jun-An; Xie, Si-Qi; Xiang, Hao-Yue; Chen, Xiao-Qing; Yang, Hua. Safety of 2-Hydroxy-4-methoxybenzaldehyde The article mentions the following:
A phosphine-mediated domino process of MBH-type reaction/umpolung γ-addition through the rational integration of the privileged reactivities of alkynoate is reported. Simply by manipulating the nucleophilic reagent, the developed protocol offers a facile, diversity-oriented construction of a wide range of three-substituted coumarins. In the part of experimental materials, we found many familiar compounds, such as 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Safety of 2-Hydroxy-4-methoxybenzaldehyde)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Safety of 2-Hydroxy-4-methoxybenzaldehyde
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