Wang, Cheng-Gang; Zhang, Yunxing; Wang, Simin; Chen, Bin; Li, Yang; Ni, Hai-Liang; Gao, Yuanji; Hu, Ping; Wang, Bi-Qin; Cao, Peng published their research in Organic Letters in 2021. The article was titled 《Nickel-Catalyzed Carboalkenylation of 1,3-Dienes with Aldehydes and Alkenylzirconium Reagents: Access to Skipped Dienes》.Computed Properties of C9H10O2 The article contains the following contents:
A regio- and stereoselective nickel-catalyzed three-component coupling reaction of aldehydes, 1,3-dienes, and alkenylzirconium reagents was realized. The ligand- and additive-free protocol afforded a convenient approach to the synthesis of skipped diene compounds bearing various functionals (e.g., hydroxyl, carbonyl, halide) and heterocyclic groups. The products were readily transformed into structurally diverse polyenes. The utility of this reaction was also demonstrated by the one-pot operation and scale-up preparation In addition to this study using 2-(Benzyloxy)acetaldehyde, there are many other studies that have used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Computed Properties of C9H10O2) was used in this study.
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) may be used in the following syntheses: (3S,5S)-methyl 6-benzyloxy-3,5-dihydroxyhexanoate ,(S)-5-benzyloxy-4-hydroxypentan-2-one, myxothiazols.Computed Properties of C9H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem