《Derivatization of Perfluorocarboxylic Acids with N,N-Dimethylformamide Dimethylacetal Prior to GC-MS Analysis》 was published in Chromatographia in 2020. These research results belong to Strozynska, Monika; Schuhen, Katrin. Recommanded Product: N,N-Dimethylformamide Dimethyl Acetal The article mentions the following:
A simple derivatization reaction with N,N-dimethylformamide di-Me acetal (DMF-DMA) was developed for the anal. of perfluorocarboxylic acids (PFCA, C4-C12) in solid samples by gas chromatog.-mass spectrometry (GC-MS). After extraction with Me tert-Bu ether (MTBE), the samples are mixed with derivatizing agent and injected into GC. The derivatization reaction takes place in injection block forming corresponding N,N,N’,N’-tetramethyl diamines. The method provides excellent separation of nine PFCA (C4-C12) in 15 min and is characterized by good precision (maximum RSD = 6.21% for 10 ng/mL, n = 6), linearity and detection limits in the range of 0.15-0.38 ng/mL. The main aim of the study was to develop a quick and easy GC-MS screening for PFCA. The method was successfully applied for sewage sludge, textiles and dental flosses. To confirm the laboratory evaluation, two samples were measured by an external laboratory using LC-MS/MS and showed comparable results. The proposed method is very promising, taking into account its simplicity, mild conditions and application of cost-effective GC-MS system. Addnl., a comparison with two other derivatization methods for PFCA: reaction with N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) and benzyl bromide is presented. After reading the article, we found that the author used N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Recommanded Product: N,N-Dimethylformamide Dimethyl Acetal)
N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Recommanded Product: N,N-Dimethylformamide Dimethyl Acetal
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