Monteith, John J.; Rousseaux, Sophie A. L. published their research in Organic Letters in 2021. The article was titled 《Ni-Catalyzed C(sp3)-O Arylation of α-Hydroxy Esters》.Recommanded Product: 2398-37-0 The article contains the following contents:
A synthesis of α-aryl ester products I [R1 = Et, Bn, Cy, etc.; R2 = H, Me, CH2Bn; R3 = Ph, 4-MeOC6H4, 4-FC6H4, etc.] via Negishi cross-coupling of α-hydroxy ester derivativesof thiocarbonyl imidazolide and aryl zinc reagents was developed. This reaction tolerated both primary and secondary C(sp3)-O alc. precursors and achieved efficient cross-coupling under Ni catalysis without the need for added external metal reductant, photocatalyst or additives. The arylation of readily accessible C(sp3)-O electrophiles in this operationally simple, rapid, and mild reaction provided a complementary way of accessing desirable α-aryl ester products I. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-methoxybenzene(cas: 2398-37-0Recommanded Product: 2398-37-0)
1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Recommanded Product: 2398-37-0
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem