《Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30》 was written by Chen, Peiran; Yang, Wenhong. Application In Synthesis of 2-Hydroxy-2-(4-propoxyphenyl)acetic acid And the article was included in Tetrahedron Letters on April 2 ,2014. The article conveys some information:
By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic mandelate esters has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 197.5. Substituent effect is briefly discussed. In the experimental materials used by the author, we found 2-Hydroxy-2-(4-propoxyphenyl)acetic acid(cas: 79694-16-9Application In Synthesis of 2-Hydroxy-2-(4-propoxyphenyl)acetic acid)
2-Hydroxy-2-(4-propoxyphenyl)acetic acid(cas: 79694-16-9) belongs to ethers.The C-O bonds that comprise simple ethers are strong. Application In Synthesis of 2-Hydroxy-2-(4-propoxyphenyl)acetic acid They are unreactive toward all but the strongest bases. Although generally of low chemical reactivity, they are more reactive than alkanes.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem