In 2019,New Journal of Chemistry included an article by Balakrishna, C.; Gudipati, Ramakrishna; Kandula, Venu; Yennam, Satyanarayana; Uma Devi, P.; Behera, Manoranjan. Electric Literature of C5H13NO2. The article was titled 《T3P mediated domino C(sp2)-H sulfenylation/annulation of enaminones and methylsulfinyls for the synthesis of chromone thioether derivatives》. The information in the text is summarized as follows:
A new regioselective method for the synthesis of 3-(methylthio)-4H-chromen-4-one I (R = H, 6-Br, 6-F, etc.) and 3-(phenylthio)-4H-chromen-4-one derivatives II (R = H, 8-F, 6-Cl, etc.; R1 = H, 4-Me, 4-Cl) has been developed. The reaction between o-hydroxy-phenyl-functionalized enaminones and methylsulfinyl derivatives using T3P gave good yields of chromone thioether derivatives The reaction proceeds via domino chromone ring construction and C(sp2)-H bond sulfenylation under transition-metal-free conditions. The experimental part of the paper was very detailed, including the reaction process of N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Electric Literature of C5H13NO2)
N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Electric Literature of C5H13NO2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem