Wang, Jiaqi; Luo, Yingying; Zhang, Yixuan; Chen, Yue; Gao, Fei; Ma, Yue; Xian, Dongmei; You, Zhonglu published their research in Journal of Coordination Chemistry in 2021. The article was titled 《Synthesis, crystal structure, and urease inhibition of an end-on azido-bridged dinuclear copper(II) complex with an oxidized tridentate Schiff base ligand》.Category: ethers-buliding-blocks The article contains the following contents:
An end-on azido-bridged dinuclear Cu(II) complex, [Cu2L2(μ1,1-N3)2], where L is the deprotonated form of N-(2-hydroxy-4-methoxybenzylidene)picolinamide (HL), was prepared by the reaction of 5-methoxy-2-[(pyridin-2-ylmethylimino)methyl]phenol (HL’) with Cu bromide and Na azide in MeOH. The structure of the complex was characterized by elemental anal., IR and UV-visible spectra, and single crystal x-ray diffraction. The complex possesses crystallog. inversion symmetry, with the two Cu ions (3.36 Å) bridged by two end-on azido bridges. Each Cu ion is in a square pyramidal coordination. The original ligand HL’ was unexpectedly oxidized to HL under mild conditions during preparation of the complex. The complex has excellent urease inhibitory activity. The experimental part of the paper was very detailed, including the reaction process of 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Category: ethers-buliding-blocks)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Category: ethers-buliding-blocks
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