《Synthesis, characterization and antibacterial effect of diarylmethylamine-based imines》 was published in Journal of Molecular Structure in 2020. These research results belong to Onur, Sultan; Kose, Muhammet; Kocer, Ferudun; Tumer, Ferhan. Safety of 2-Hydroxy-4-methoxybenzaldehyde The article mentions the following:
Firstly, starting from benzoic acid, the diarylmethanone compound (4-methylphenyl)(phenyl)methanone was synthesized. The diarylmethanone (4-methylphenyl)(phenyl)methanone was converted to the corresponding oxime N-[(4-methylphenyl)(phenyl)methylidene]hydroxylamine and then reduced to the diarylmethylamine compd (4-methylphenyl)(phenyl)methanamine. Four different imine compounds2-OH-3-R1-4-R2C6H2CH=NCH(4-CH3C6H5)C6H4(R1 = H, OH, OMe; R2 = H, OH, OMe) were obtained from the condensation of the (4-methylphenyl)(phenyl)methanamine with four different salicylaldehyde 2-OH-3-R1-4-R2C6H2CHO. Antimicrobial activities against Gram (+) and Gram (-) microorganisms (Staphylococcus aureus, Bacillus cereus as the Gram (+); Escherichia coli and Salmonella typhimurium as the Gram (-); and Candida albicans as the fungi) were investigated. In the experiment, the researchers used many compounds, for example, 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Safety of 2-Hydroxy-4-methoxybenzaldehyde)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.Safety of 2-Hydroxy-4-methoxybenzaldehyde
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem