Mekky, Ahmed E. M.; Ahmed, Mohamed S. Mohamed; Sanad, Sherif M. H.; Abdallah, Zeinab A. published an article in 2021. The article was titled 《Bis(benzofuran-enaminone) hybrid possessing piperazine linker: Versatile precursor for microwave assisted synthesis of bis(pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidines)》, and you may find the article in Synthetic Communications.Recommanded Product: 4637-24-5 The information in the text is summarized as follows:
Herein efficient procedures for the synthesis of new piperazine-linked bis(pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidines) using bis(benzofuran-enaminone) hybrid as a key intermediate are reported. For this purpose, bis(enaminone) was reacted with a new series of 3-amino-4-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridines in pyridine under microwave irradiation at 120° for 90 min to afford the target bis(pyrimidines). In a two-steps synthetic route, bis(enaminone) was used to prepare a novel bis(3-amino-1H-pyrazolo[3,4-b]pyridine). Next, the former hybrid was reacted with two equivalent of the appropriate enaminones as well as arylidinemalononitriles in pyridine under microwave irradiation at 120° for 2 h to afford the target bis(pyrimidines). Furthermore, a mixture of bis(pyrazolopyridine) reacted with two equivalent of 1,3-diketones and β-ketoesters in glacial acetic acid was microwave irradiated at 130° for 90 min to give bis(2,4-disubstituted pyrimidines) and bis(2-substituted pyrimidin-4(1H)-ones), resp. The structures of the new hybrids were confirmed via considering their elemental analyses as well as their spectral data. In the part of experimental materials, we found many familiar compounds, such as N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Recommanded Product: 4637-24-5)
N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds. Reduction of nitriles and oximes (R2C=NOH) also yields primary amines.Recommanded Product: 4637-24-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem