Product Details of 135-02-4In 2020 ,《H5BW12O40-Catalyzed syntheses of 1,4-dihydropyridines and polyhydroquinolines via Hantzsch reaction: Joint experimental and computational studies》 appeared in Journal of Molecular Structure. The author of the article were Momeni, Tayebeh; Heravi, Majid M.; Hosseinnejad, Tayebeh; Mirzaei, Masoud; Zadsirjan, Vahideh. The article conveys some information:
A series of polyhydroquinoline derivatives I [RR1 = C(O)CH2C(Me2)CH2; Ar = Ph, 4-OMeC6H4, 3-O2NC6H4, etc.] was effectively synthesized via Hantzsch reaction of benzaldehydes, Et acetoacetate, dimedone and ammonium acetate in high yields in the presence of catalytic amounts of a highly neg. charged borotungstic acid H5BW12O40 in refluxing EtOH under green and mild reaction conditions. This method was also used for the synthesis of 1,4-dihydropyridines I [R = CO2Et; R1 = Me] via reaction of benzaldehydes, Et acetoacetate and ammonium acetate. Borotungstic acid is a Keggin-type heteropoly acid with a higher neg. charge and strong Bronsted acidity. Moreover, a comparative mechanistical anal. of Hantzsch reaction was made based on the structural, thermodynamical and electronic properties along with the reaction pathway using d. functional theory (DFT) and quantum theory of atoms in mols. (QTAIM) approaches.2-Methoxybenzaldehyde(cas: 135-02-4Product Details of 135-02-4) was used in this study.
2-Methoxybenzaldehyde(cas: 135-02-4) is found in cassia oil, cinnamon bark, and cinnamon bark oil. It is a clear colorless liquid with a strong aroma. It has been used to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae.Product Details of 135-02-4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem