In 2019,Chemistry – A European Journal included an article by Magne, Valentin; Ball, Liam T.. Electric Literature of C7H7IO. The article was titled 《Synthesis of Air-stable, Odorless Thiophenol Surrogates via Ni-Catalyzed C-S Cross-Coupling》. The information in the text is summarized as follows:
An efficient catalytic method for the preparation of S-(hetero)aryl isothiouronium salts ArSC(NH2)=NH2+ 3,5-(NO2)2C6H3C(O)O- (Ar = Ph, thiophen-2-yl, 1H-pyrazol-4-yl, etc.) and demonstrates that these air-stable, odorless solids serving as user-friendly sources of thiophenols have been synthesized. Diverse isothiouronium salts featuring synthetically useful functionality are readily accessible by nickel-catalyzed C-S cross-coupling of (hetero)aryl iodides ArI and thiourea. Convenient, chromatog.-free isolation of these salts is achieved by precipitation, allowing the methodol. to be applied directly to large scales. Thiophenols are liberated from the corresponding isothiouronium salts upon treatment with a weak base, enabling an in situ release/S-functionalization strategy that entirely negates the need to isolate, purify or manipulate these noxious reagents. In the experiment, the researchers used 1-Iodo-2-methoxybenzene(cas: 529-28-2Electric Literature of C7H7IO)
1-Iodo-2-methoxybenzene(cas: 529-28-2) is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.Electric Literature of C7H7IO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem