The author of 《Nickel-Catalyzed Construction of 2,4-disubstituted Imidazoles via C-C Coupling and C-N Condensation Cascade Reactions》 were Fang, Shengyang; Yu, Haihua; Yang, Xicheng; Li, Jianqi; Shao, Liming. And the article was published in Advanced Synthesis & Catalysis in 2019. Synthetic Route of C7H9BO3 The author mentioned the following in the article:
A convenient Ni(II)-catalyzed C-C and C-N cascade coupling reaction was developed to directly access various 2,4-disubstituted imidazoles [e.g., N-(cyanomethyl)acetamide + phenylboronic acid → 2-methyl-4-phenyl-1H-imidazole (87%)]. The reaction scope covers a variety of aryl and aliphatic substitutions, which demonstrate moderate-to-excellent yields. The tolerance of halogen and N-containing heterocyclic groups demonstrates the versatility of this method for further synthetic explorations. The experimental part of the paper was very detailed, including the reaction process of 3-Methoxyphenylboronic acid(cas: 10365-98-7Synthetic Route of C7H9BO3)
3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Synthetic Route of C7H9BO3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem