Yu, Xiaoye; Daniliuc, Constantin G.; Alasmary, Fatmah Ali; Studer, Armido published an article in 2021. The article was titled 《Direct Access to α-Aminosilanes Enabled by Visible-Light-Mediated Multicomponent Radical Cross-Coupling》, and you may find the article in Angewandte Chemie, International Edition.Electric Literature of C9H10O2 The information in the text is summarized as follows:
α-Aminosilanes are an important class of organic compounds that show biol. activity. A new approach to α-aminosilanes that uses photoredox catalysis to enable three-component coupling of organo(tristrimethylsilyl)silanes with feedstock alkylamines and aldehydes is presented. A wide range of highly functionalized α-aminosilanes can be obtained in good yields under mild conditions. Both primary amines and secondary amines are compatible with this transformation. Also, optically pure α-aminosilanes are accessible by using chiral amines. Mechanistic studies indicate that reactions proceed through radical/radical cross-coupling of silyl radicals with α-amino alkyl radicals.2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Electric Literature of C9H10O2) was used in this study.
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Electric Literature of C9H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem