Yu, Jianjin; Li, Chao-Jun; Zeng, Huiying published an article in 2021. The article was titled 《Dearomatization-Rearomatization Strategy for ortho-Selective Alkylation of Phenols with Primary Alcohols》, and you may find the article in Angewandte Chemie, International Edition.Category: ethers-buliding-blocks The information in the text is summarized as follows:
Phenols are common precursors and core structures of a variety of industrial chems. ranging from pharmaceuticals to polymers. However, the synthesis of site-specifically substituted phenols is challenging, and thus the development of new methods for this purpose would be highly desirable. Reported here is a protocol for palladium-catalyzed ortho-selective alkylation reactions of phenols with primary alcs. by a dearomatization-rearomatization strategy, with water as the sole byproduct. Various substituted phenols and primary alcs. were compatible with the standard reaction conditions. The detailed mechanism of this transformation was also investigated. After reading the article, we found that the author used m-Methoxyphenol(cas: 150-19-6Category: ethers-buliding-blocks)
m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem