In 2019,Research on Chemical Intermediates included an article by Salami, Masoumeh; Ezabadi, Ali. Application In Synthesis of 2-Methoxybenzaldehyde. The article was titled 《A caffeine-based ionic liquid as a novel and eco-friendly catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions》. The information in the text is summarized as follows:
A new Bronsted acidic ionic liquid has been synthesized using caffeine and p-toluenesulfonic acid as precursors. The IL was fully characterized by FT-IR, 1H NMR, 13C NMR, MS, elemental anal., as well as Hammett acidity function. The prepared reagent is efficiently able to catalyze the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions. Various advantages associated with this method include novelty and easy preparation of catalyst, simple work-up procedure and purification, short reaction times, high product yields, and easy recovery and reusability of the catalyst. After reading the article, we found that the author used 2-Methoxybenzaldehyde(cas: 135-02-4Application In Synthesis of 2-Methoxybenzaldehyde)
2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.Application In Synthesis of 2-Methoxybenzaldehyde
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem