In 2019,Physical Chemistry Chemical Physics included an article by Lopez, Juan C.; Perez, Cristobal; Blanco, Susana; Shubert, V. Alvin; Temelso, Berhane; Shields, George C.; Schnell, Melanie. Recommanded Product: 1,4,7,10,13-Pentaoxacyclopentadecane. The article was titled 《Water induces the same crown shapes as Li+ or Na+ in 15-crown-5 ether: a broadband rotational study》. The information in the text is summarized as follows:
15-Crown-5 ether (15C5) and its complexes with water have been studied using broadband Fourier transform microwave spectroscopy in a supersonic jet. A new conformer of 15C5 has been observed and established as the new global min. out of a total of nine isolated structures. In addition, two 15C5-H2O and two 15C5-(H2O)2 clusters have been observed The cluster structures have been unambiguously identified through the observation of water 18O isotopologue spectra. In all the clusters, at least one water mol., located close to the axis of the 15C5 ring, interacts through two simultaneous hydrogen bonds to the endocyclic oxygen atoms. This interaction reshapes the 15C5 ring to reduce its rich conformational landscape to only two open structures, related to those found in complexes with Li+ or Na+ ions. In the most abundant 15C5-(H2O)2 form, the two water mols. repeat the same interaction scheme while binding to opposite sides of the ring. In the second most abundant dihydrated form the two water mols. lie on the same side of the ring. This finding is exceptionally rare because water-water interactions typically prevail over the formation of addnl. solute-water contacts, and it showcases the particular binding features of crown ethers. In the part of experimental materials, we found many familiar compounds, such as 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Recommanded Product: 1,4,7,10,13-Pentaoxacyclopentadecane)
1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Recommanded Product: 1,4,7,10,13-Pentaoxacyclopentadecane
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem