Li, Sanliang; Chen, Qiaoyu; Yang, Junfeng; Zhang, Junliang published an article in 2022. The article was titled 《Palladium-Catalyzed Enantioselective γ-Arylation of β,γ-Unsaturated Butenolides》, and you may find the article in Angewandte Chemie, International Edition.Formula: C7H7BrO The information in the text is summarized as follows:
An efficient Pd-catalyzed enantioselective γ-arylation of β,γ-unsaturated butenolides with aryl bromides R1Br (R1 = Ph, naphthalen-1-yl, thiophen-2-yl, etc.), which shows high γ-selectivity, good functional group tolerance and excellent enantioselectivity, to give I (R2 = Me, Bn, cyclohexyl, etc.) was reported. Notably, this protocol also allows for facile construction of tricyclic tetrahydroindolines and tetrahydroisoquinolinones, e.g., II, in one step. DFT calculations are consistent with the exptl. results, suggesting that the γ-arylation is favored over the α-arylation. Finally, this method is applied to the rapid synthesis of natural product (R)-(+)-boivinianin A. In addition to this study using 1-Bromo-3-methoxybenzene, there are many other studies that have used 1-Bromo-3-methoxybenzene(cas: 2398-37-0Formula: C7H7BrO) was used in this study.
1-Bromo-3-methoxybenzene(cas: 2398-37-0) is a compound useful in organic synthesis and other chemical processes. It is an intermediate used for pharmaceuticals, perfumes and agrochemicals.Formula: C7H7BrO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem