In 2022,Larnaud, Florent; Calata, Charlene; Prunier, Anais; Le Guen, Clothilde; Legay, Remi; Pfund, Emmanuel; Lequeux, Thierry published an article in Organic & Biomolecular Chemistry. The title of the article was 《Convergent access to mono-fluoroalkene-based peptidomimetics》.SDS of cas: 60656-87-3 The author mentioned the following in the article:
The convergent and selective preparation of (Z)-monofluoroalkene-based dipeptide isosteres from functionalized fluorosulfones as a cornerstone is described. In this approach, the N-terminal amino group is introduced by a conjugate addition reaction of phthalimide onto fluorinated vinylsulfones containing α-amino-acid side chains while the C-terminal motif is linked to the fluorovinylic peptide bond mimic via the Julia-Kocienski reaction between fluorosulfones and substituted aldehydes bearing α-amino-acid side chains. In the experimental materials used by the author, we found 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3SDS of cas: 60656-87-3)
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).SDS of cas: 60656-87-3
Referemce:
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Ether | (C2H5)2O – PubChem