Related Products of 150-19-6In 2020 ,《Access to Vinyl Ethers and Ketones with Hypervalent Iodine Reagents as Oxy-Allyl Cation Synthetic Equivalents》 was published in Angewandte Chemie, International Edition. The article was written by Declas, Nina; Waser, Jerome. The article contains the following contents:
We report an Umpolung strategy of enol ethers to generate oxy-allyl cation equivalent based on the use of hypervalent iodine reagents. Under mild basic conditions, the addition of nucleophiles to aryloxy-substituted vinylbenziodoxolone (VBX) reagents, easily available in two steps from silyl alkynes, resulted in the stereoselective formation of substituted aryl enol ethers. The reaction was most efficient with phenols as nucleophiles, but preliminary results were also achieved for C- and N- nucleophiles. In absence of external nucleophiles, the 2-iodobenzoate group of the reagent was transferred. The obtained aryl enol ethers could then be transformed into α-difunctionalized ketones by oxidation The described “”allyl cation””-like reactivity contrast with the well-established “”vinyl-cation”” behavior of alkenyl iodonium salts. Thus, e.g., reaction of I with p-cresol afforded allyl ether II (80%) in DME with KOtBu as base; in absence of external nucleophile, allylic ester III was obtained (65%). In the experiment, the researchers used m-Methoxyphenol(cas: 150-19-6Related Products of 150-19-6)
m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Related Products of 150-19-6
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem