In 2019,Nature (London, United Kingdom) included an article by Berger, Florian; Plutschack, Matthew B.; Riegger, Julian; Yu, Wanwan; Speicher, Samira; Ho, Matthew; Frank, Nils; Ritter, Tobias. Application of 10365-98-7. The article was titled 《Site-selective and versatile aromatic C-H functionalization by thianthrenation》. The information in the text is summarized as follows:
Direct C-H functionalization can quickly increase useful structural and functional mol. complexity. Site selectivity can sometimes be achieved through appropriate directing groups or substitution patterns-in the absence of such functionality, most aromatic C-H functionalization reactions provide more than one product isomer for most substrates. Development of a C-H functionalization reaction that proceeds with high positional selectivity and installs a functional group that can serve as a synthetic linchpin for further functionalization would provide access to a large variety of well-defined arene derivatives Here we report a highly selective aromatic C-H functionalization reaction that does not require a particular directing group or substitution pattern to achieve selectivity, and provides functionalized arenes that can participate in various transformations. We introduce a persistent sulfur-based radical to functionalize complex arenes with high selectivity and obtain thianthrenium salts, e.g., I that are ready to engage in different transformations, via both transition-metal and photoredox catalysis. This transformation differs fundamentally from all previous aromatic C-H functionalization reactions in that it provides direct access to a large number of derivatives of complex small mols., quickly generating functional diversity with selectivity that is not achievable by other methods. In the experiment, the researchers used 3-Methoxyphenylboronic acid(cas: 10365-98-7Application of 10365-98-7)
3-Methoxyphenylboronic acid(cas: 10365-98-7) belongs to boronic acids. Boronic acids are mild Lewis acids which are generally stable and easy to handle, making them important to organic synthesis.Application of 10365-98-7
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem