《Synthesis and Anti-Microbial Activity of Benzylidenhydrazides of Glycyrrhetic Acid》 was written by Baltina, L. A.; Kondratenko, R. M.; Bulgakov, A. K.. COA of Formula: C8H8O2 And the article was included in Russian Journal of Bioorganic Chemistry in 2020. The article conveys some information:
New derivatives of glycyrrhetic acid with hydrazide pharmacophore groups I (R = C6H5, 4-HOC6H4, 4-MeOC6H4, 2-MeOC6H4, 4-(Me)2NC6H3) were synthesized and their antimicrobial activity was evaluated. Compound I (R = 4-HOC6H4) exhibited the highest antimicrobial activity. This compound had both an antibacterial effect against Escherichia coli, Proteus vulgaris, Klebsiella pneumonia, Staphylococcus aureus, Citrobacter diversus, Enterobacter aerogenes, Pseudomonas aeruginosa, and Enterobacter cloacae and antifungal activity against the Candida albicans fungus. The min. inhibitory concentrations of this compound and pimafucin were similar for Candida albicans. In the part of experimental materials, we found many familiar compounds, such as 2-Methoxybenzaldehyde(cas: 135-02-4COA of Formula: C8H8O2)
2-Methoxybenzaldehyde(cas: 135-02-4) is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, chewing gum, confections, frozen dairy, fruit ices, hard/soft candy, instant coffee, tea, Jams, jellies, and milk products. It also has been used to obtain good enantioselectivities using Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding in asymmetric Henry reaction.COA of Formula: C8H8O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem