Mohamed, Salah E. N.; Whiting, Donald A. published the artcile< Synthesis of meta,meta-bridged biaryls [7,0-metacyclophanes] via aryl-aryl coupling: factors affecting the cyclization>, Name: 4-(4-Methoxyphenyl)-1-butanol, the main research area is iodoarylheptane cyclization; metacycloptane.
Isoxazoline I and 3,4-I(MeO)C6H3(CH2)4CH(OAc)(CH2)2C6H3(OMe)I-4,3 were prepared; on treatment with (Ph3P)4Ni in DMF at 55-65° for 48 h these compounds cyclized to the [7.0]metacyclophanes II and III, resp., in 31 and 49% yield, resp. The analog 3,4-I(MeO)C6H3(CH2)4SO2(CH2)3C6H3(OMe)I-4,3 was also prepared; it failed to cyclize. Steric effects at the coupling site are more important than torsional strain in the products in determination of the product yield.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about Cyclocondensation reaction, intramolecular. 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Name: 4-(4-Methoxyphenyl)-1-butanol.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem