Maillard, Ludovic T.; Benohoud, Meryem; Durand, Philippe; Badet, Bernard published the artcile< A New Supported Reagent for the Parallel Synthesis of Primary and Secondary O-Alkyl Hydroxylamines through a Base-Catalyzed Mitsunobu Reaction>, Formula: C11H16O2, the main research area is supported hydroxyphthalimide parallel synthesis hydroxylamine Mitsunobu reaction; alkylation Mitsunobu alc polymer supported hydroxyphthalimide.
The growing field of applications of O-alkyl hydroxylamines in medicinal chem. and chem. biol. has motivated the search for a parallel synthesis. A solid-phase approach based on the alkylation by alcs. of a new supported N(hydroxy)phthalimide reagent using a Mitsunobu reaction followed by methylaminolysis was optimized. This study points out the importance of the linker and a specific base effect for the Mitsunobu reaction. A large variety of alcs. can be used to give with moderate to high yields diverse O-alkyl hydroxylamines in high purity.
Journal of Organic Chemistry published new progress about Hydroxylamines Role: SPN (Synthetic Preparation), PREP (Preparation) (O-alkyl derivatives). 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Formula: C11H16O2.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem