《Distinctive Viewpoint on the Rapid Dissolution Mechanism of α-Chitin in Aqueous Potassium Hydroxide-Urea Solution at Low Temperatures》 was published in Macromolecules (Washington, DC, United States) in 2020. These research results belong to Huang, Junchao; Zhong, Yi; Zhang, Lina; Cai, Jie. Recommanded Product: 33100-27-5 The article mentions the following:
To develop a green solvent for chitin dissolution, the most fundamental aspects of its mechanism must be elucidated. In this work, an aqueous KOH/urea solution was utilized for the rapid dissolution of α-chitin without performing freeze-thaw cycles. It was found that the mechanism of α-chitin dissolution involved not only the fast expansion of its crystalline regions and hierarchical structure but also direct and strong interactions between K+ ions and chitin carbonyl oxygens. The relatively high flexibility and deformability of the K+ hydration shells allowed fast exchange between water mols. and carbonyl oxygens, which induced the cleavage of strong inter- and intramol. hydrogen bonds, resulting in the rapid swelling and destruction of the chitin crystal and dissolution of α-chitin. Moreover, the addnl. urea mitigated the hydrophobicity of chitin chains, which prevented self-aggregation and increased the mobility of chitin chains. The described α-chitin dissolution mechanism can help achieve a better understanding of biomacromol. dissolution The experimental part of the paper was very detailed, including the reaction process of 1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5Recommanded Product: 33100-27-5)
1,4,7,10,13-Pentaoxacyclopentadecane(cas: 33100-27-5) is a member of crown ether Ligands. Crown-ethers are macrocyclic polyethers capable of forming host-guest complexes, especially with inorganic and organic cations. Crown-ethers can incorporate protonated primary amine compounds by formation of ion-dipole bonds with the oxygen atoms of the chiral selector. Crown-ethers have been widely used for the separation of several pharmaceuticals both in aqueous and non-aqueous media. Recommanded Product: 33100-27-5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem