Application of 150-19-6In 2021 ,《Exploring the Assembly of Resorc[4]arenes for the Construction of Supramolecular Nano-Aggregates》 appeared in International Journal of Molecular Sciences. The author of the article were Buonsenso, Fabio; Ghirga, Francesca; Romeo, Isabella; Siani, Gabriella; Pilato, Serena; Quaglio, Deborah; Pierini, Marco; Botta, Bruno; Calcaterra, Andrea. The article conveys some information:
Many biol. active compounds feature low solubility in aqueous media and, thus, poor bioavailability. The formation of the host-guest complex by using calixarene-based macrocycles (i.e., resorcinol-derived cyclic oligomers) with a good solubility profile can improve solubilization of hydrophobic drugs. Herein, we explore the ability of resorc[4]arenes to self-assemble in polar solutions, to form supramol. aggregates, and to promote water-solubility of an isoflavone endowed with anti-cancer activity, namely Glabrescione B (GlaB). Accordingly, we synthesized several architectures featuring a different pattern of substitution on the upper rim including functional groups able to undergo acid dissociation (i.e., carboxyl and hydroxyl groups). The aggregation phenomenon of the amphiphilic resorc[4]arenes has been investigated in a THF/water solution by UV-visible spectroscopy, at different pH values. Based on their ionization properties, we demonstrated that the supramol. assembly of resorc[4]arene-based systems can be modulated at given pH values, and thus promoting the solubility of GlaB. In addition to this study using m-Methoxyphenol, there are many other studies that have used m-Methoxyphenol(cas: 150-19-6Application of 150-19-6) was used in this study.
m-Methoxyphenol(cas: 150-19-6) may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.Application of 150-19-6
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem