Gharpure, Santosh J.; Jegadeesan, S.; Vishwakarma, Dharmendra S. published an article in 2021. The article was titled 《Acid-catalysed iterative generation of o-quinone methides for the synthesis of dioxabicyclo[3.3.1]nonanes: total synthesis of myristicyclins A-B》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Recommanded Product: 673-22-3 The information in the text is summarized as follows:
A practical and efficient method for the synthesis of bioactive flavanoids relying on the strategic use of o-quinine methide (o-QM) intermediates was reported. This involved Bronsted acid-catalyzed iterative generation of o-QMs/[4+2] cycloaddition/intermol. Michael addition/cyclative acetalization in a cascade sequence for the synthesis of dioxabicyclo[3.3.1]nonanes I [R1 = H, 7-OMe, 8-OMe; R2 = H, CO2Me, CO2Et; R3 = H, Me, Ph, etc.]. The ‘one-pot’, controlled cascade sequence successfully provided the shortest route amenable for gram scale synthesis of natural products (±)-myristicyclins A-B II and III. In the experimental materials used by the author, we found 2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3Recommanded Product: 673-22-3)
2-Hydroxy-4-methoxybenzaldehyde(cas: 673-22-3) is the main component of root bark essential oil of Periploca sepium Bunge. It is a potential tyrosinase inhibitor present in African medicinal plants. 2-Hydroxy-4-methoxybenzaldehyde was used in the synthesis of Schiff base ligand.Recommanded Product: 673-22-3
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