Chen, Yuan’s team published research in Asian Journal of Organic Chemistry in 2021-03-31 | 10541-78-3

Asian Journal of Organic Chemistry published new progress about Bond formation (C-Br, C-C, C=O). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Product Details of C8H11NO.

Chen, Yuan; Lu, Fo-Yun; Li, Rui-Xue; Guan, Zhi; He, Yan-Hong published the artcile< Visible-light-mediated Synthesis of Bromo-containing Azaspirotrienediones from N-phenylpropynamides>, Product Details of C8H11NO, the main research area is bromo azaspirotrienedione preparation photochem green chem; phenylpropynamide tandem radical addition ipsocyclization oxidation photocatalyst.

A visible-light-mediated reaction of N-phenylpropynamides 2-R1-3-R2C6H3N(R3)C(=O)CCR4 (R1 = H, Me, OMe; R2 = H, Me, CF3, Cl, F, Br; R1R2 = -CH=CHCH=CH-; R3 = Me, Et, i-Pr, Bn; R4 = Ph, 3-MeOC6H4, 4-MeOC6H4, 4-MeC6H4, 4-CF3C6H4, 4-FC6H4, 4-ClC6H4, 4-BrC6H4) and 1-(3,4-dihydro-1(2H)-quinolinyl)-3-phenyl-2-propyn-1-one with di-Et 2,2-dibromomalonate for the synthesis of bromo-substituted azaspirotrienediones I and II has been developed. This method allows the formation of C-Br, C-C and C=O bonds in one pot via a cascade radical addition/ipso-cyclization/oxidation process. A possible radical mechanism involving single electron transfer and energy transfer processes is proposed based on control experiments, cyclic voltammetry determination and Stern-Volmer quenching experiments

Asian Journal of Organic Chemistry published new progress about Bond formation (C-Br, C-C, C=O). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Product Details of C8H11NO.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem