Pingali, Harikishore; Jain, Mukul; Shah, Shailesh; Basu, Sujay; Makadia, Pankaj; Goswami, Amitgiri; Zaware, Pandurang; Patil, Pravin; Godha, Atul; Giri, Suresh; Goel, Ashish; Patel, Megha; Patel, Harilal; Patel, Pankaj published the artcile< Discovery of a highly orally bioavailable c-5-[6-(4-methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent>, Safety of 4-(4-Methoxyphenyl)-1-butanol, the main research area is methanesulfonylhexyldioxanecarboxylic acid preparation hypoglycemic hypolipidemic.
A series of novel 1,3-dioxane-2-carboxylic acid derivatives containing alkyl chain tether and substituted Ph group as a lipophilic tail have been prepared as agonists of PPARα and γ. C-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid exhibited potent hypoglycemic and lipid lowering activity with high oral bioavailability in animal models.
Bioorganic & Medicinal Chemistry Letters published new progress about Antidiabetic agents. 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Safety of 4-(4-Methoxyphenyl)-1-butanol.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem