Nouaille, Augustin; Pannecoucke, Xavier; Poisson, Thomas; Couve-Bonnaire, Samuel published the artcile< Access to Trisubstituted Fluoroalkenes by Ruthenium-Catalyzed Cross-Metathesis>, Name: 4-(4-Methoxyphenyl)-1-butanol, the main research area is trisubstituted fluoroalkene preparation stereoselective ruthenium catalyst; terminal alkene fluoroalkene cross metathesis.
Although the olefin metathesis reaction is a well-known and powerful strategy to get alkenes, this reaction remained highly challenging with fluororalkenes, especially the Cross-Metathesis (CM) process. Author’s thought was to find an easy accessible, convenient, reactive and post-functionalizable source of fluoroalkene, found as the Me 2-fluoroacrylate. Authors reported herein the efficient ruthenium-catalyzed CM reaction of various terminal and internal alkenes with Me 2-fluoroacrylate giving access, for the first time, to trisubstituted fluoroalkenes stereoselectively. Unprecedent TON for CM involving fluoroalkene, up to 175, have been obtained and the reaction proved to be tolerant and effective with a large range of olefin partners giving fair to high yields in metathesis products.
Advanced Synthesis & Catalysis published new progress about Catalysis. 52244-70-9 belongs to class ethers-buliding-blocks, and the molecular formula is C11H16O2, Name: 4-(4-Methoxyphenyl)-1-butanol.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem