Chakrabarti, Kaushik; Dutta, Kuheli; Kundu, Sabuj published the artcile< Synthesis of N-methylated amines from acyl azides using methanol>, Safety of 2-Methoxy-N-methylaniline, the main research area is methylated amine preparation acyl azide methanol Curtius rearrangement.
The transformation of acyl azide derivatives into N-methylamines was developed using methanol as the C1 source via the one-pot Curtius rearrangement and borrowing hydrogen methodol. Following this protocol, various functionalized N-methylated amines were synthesized using the (NNN)Ru(II) complex from carboxylic acids via an acyl azide intermediate. Several kinetic studies and DFT calculations were carried out to support the mechanism and also to determine the role of the Ru(II) complex and base in this transformation.
Organic & Biomolecular Chemistry published new progress about Acyl azides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 10541-78-3 belongs to class ethers-buliding-blocks, and the molecular formula is C8H11NO, Safety of 2-Methoxy-N-methylaniline.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem