Cano, Carolina; Pavon, Javier; Serrano, Antonia; Goya, Pilar; Paez, Juan Antonio; Rodriguez de Fonseca, Fernando; Macias-Gonzalez, Manuel published the artcile< Novel Sulfamide Analogs of Oleoylethanolamide Showing In Vivo Satiety Inducing Actions and PPARα Activation>, Electric Literature of 10305-42-7, the main research area is sulfamide oleoylethanolamide analog preparation peroxisome proliferator activated receptor.
Long chain saturated and unsaturated alkyl sulfamide and Pr sulfamide derivatives, analogs of oleoylethanolamide, were synthesized and evaluated in vivo and in vitro as peroxisome proliferator activated receptor alpha (PPARα) activators. Addnl., the anorexic effects of the new compounds were studied in vivo in food-deprived rats. Among the active compounds N-octadecyl-N’-propylsulfamide was identified as a potent hypolipidemic compound, a potent feeding suppressant, and a concentration-dependent activator of PPARα.
Journal of Medicinal Chemistry published new progress about Peroxisome proliferator-activated receptor α Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 10305-42-7 belongs to class ethers-buliding-blocks, and the molecular formula is C3H8ClNO2S, Electric Literature of 10305-42-7.
Referemce:
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Ether | (C2H5)2O – PubChem