Month: September 2022

Related Products of 2657-87-6In 2022, Zhang, Hao-Yang;Yuan, Li-Li;Hong, Wei-Jie;Yang, Shi-Yong published 《Improved Melt Processabilities of Thermosetting Polyimide Matrix Resins for High Temperature Carbon Fiber Composite Applications》. 《Polymers (Basel, Switzerland)》published the findings. The article contains the following contents:

With the goal of improving processability of imide oligomers and achieving of high temperature carbon fiber composite, a series of Thermosetting Matrix Resin solutions (TMR) were prepared by polycondensation of aromatic diamine (3,4′-oxybisbenzenamine, 3,4-ODA) and diester of biphenylene diacid (BPDE) using monoester of 4-phenylethynylphthalic acid (PEPE) as end-capping agent in Et alc. as solvent to afford phenylethynyl-endcapped poly(amic ester) resins with calculated mol. weight (Calc’d Mw) of 1500-10,000. Meanwhile, a series of reactive diluent solutions (RDm) with Calc’d Mw of 600-2100 were also prepared derived from aromatic diamine (4,4′-oxybisbenzenamine, 4,4-ODA), diester of asym. biphenylene diacid (α-BPDE) and monoester of 4-phenylethynylphthalic acid (PEPE) in Et alc. Then, the TMR solution was mixed with the RDm solution at different weight ratios to afford a series of A-staged thermosetting blend resin (TMR/RDm) solutions for carbon fiber composites. Exptl. results demonstrated that the thermosetting blend resins exhibited improved melt processability and excellent thermal stability. After being thermally treated at 200°C/1 h, the B-staged TMR/RDm showed very low melt viscosities and wider processing window. The min. melt viscosities of ≤50 Pa·s was measured at ≤368°C and the temperature scale at melt viscosities of ≤100 Pa·s were detected at 310-390°C, resp. The thermally cured neat resins at 380°C/2 h showed a great combination of mech. and thermal properties, including tensile strength of 84.0 MPa, elongation at breakage of 4.1%, and glass transition temperature (T_g) of 423°C, successively. The carbon fiber reinforced polyimide composite processed by autoclave technique exhibited excellent mech. properties both at room temperature and 370°C. This study paved the way for the development of high-temperature resistant carbon fiber resin composites for use in complicated aeronautical structures. And 3-(4-Aminophenoxy)aniline (cas: 2657-87-6) was used in the research process.

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. Related Products of 2657-87-6Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gros, Philippe;Le Perchec, Pierre;Senet, Jean-Pierre published 《Silica-supported guanidinium chloride-acetyl chloride as an efficient deprotecting reagent for acetals》 in 1995. The article was appeared in 《Journal of Chemical Research, Synopses》. They have made some progress in their research.HPLC of Formula: 2235-01-0 The article mentions the following:

Acetals have been treated with acetyl chloride in the presence of catalytic amounts of silica-supported guanidinium chloride to produce the corresponding aldehydes and ketones in good yields under neutral conditions. And Dimethoxydiphenylmethane (cas: 2235-01-0) was used in the research process.

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. HPLC of Formula: 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Sorlin, Alexandre M.;Mixdorf, Jason C.;Rotella, Madeline E.;Martin, Robert T.;Gutierrez, Osvaldo;Nguyen, Hien M. published 《The Role of Trichloroacetimidate To Enable Iridium-Catalyzed Regio- and Enantioselective Allylic Fluorination: A Combined Experimental and Computational Study》 in 2019. The article was appeared in 《Journal of the American Chemical Society》. They have made some progress in their research.Related Products of 2235-01-0 The article mentions the following:

Asym. allylic fluorination has proven to be a robust and efficient methodol. with potential applications for the development of pharmaceuticals and practical synthesis for ¹⁸F-radiolabeling. A combined computational (dispersion-corrected DFT) and exptl. approach was taken to interrogate the mechanism of the diene-ligated, iridium-catalyzed regio- and enantioselective allylic fluorination. Our group has shown that, in the presence of an iridium(I) catalyst and nucleophilic fluoride source (Et₃N·3HF), allylic trichloroacetimidates undergo rapid fluoride substitution to generate allylic fluoride products with excellent levels of branched-to-linear ratios. Mechanistic studies reveal the crucial role of the trichloroacetimidate as a potent leaving group and ligand to enable conversion of racemic allylic trichloroacetimidates to the corresponding enantioenriched allylic fluorides, via a dynamic kinetic asym. transformation (DYKAT), in the presence of the chiral bicyclo[3.3.0]octadiene-ligated iridium catalyst. And Dimethoxydiphenylmethane (cas: 2235-01-0) was used in the research process.

The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.Related Products of 2235-01-0

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Iwashita, Kenichi;Katoh, Hironobu;Ohta, Yoshihiro;Yokozawa, Tsutomu published 《Photodeprotectable N-alkoxybenzyl aromatic polyamides》. The research results were published in《Polymers (Basel, Switzerland)》 in 2017.Quality Control of 3-(4-Aminophenoxy)aniline The article conveys some information:

N-alkoxybenzyl aromatic polyamides were synthesized by polycondensation of N-alkoxybenzyl aromatic diamine with equimolar dicarboxylic acid chloride in the presence of 2.2 equivalent of pyridine at room temperature for 2 days. The obtained polyamides were mainly cyclic polymers, as determined by means of matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry, and showed higher solubility in organic solvents than unprotected aromatic polyamides. Photodeprotection of N-alkoxybenzyl aromatic polyamide film containing photo acid generator (PAG) proceeded well under UV irradiation (5 J/cm²), followed by heating at 130 °C for 15 min. The nature of the polymer end groups of N-alkoxybenzyl aromatic polyamides was found to be crucial for photodeprotection reactivity. These polymers are promising candidates for photosensitive heat-resistant materials for fine Cu wiring formation by electroless Cu plating of high-d. semiconductor packaging substrates. To complete the study, the researchers used 3-(4-Aminophenoxy)aniline (cas: 2657-87-6) .

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Quality Control of 3-(4-Aminophenoxy)aniline The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Shen, Xingyuan;Connolly, Timothy;Huang, Yuhui;Colvin, Michael;Wang, Changchun;Lu, Jennifer published 《Adjusting Local Molecular Environment for Giant Ambient Thermal Contraction》. The research results were published in《Macromolecular Rapid Communications》 in 2016.Application In Synthesis of 3-(4-Aminophenoxy)aniline The article conveys some information:

A low-energy triggered switch that can generate mechanoresponse has great technol. potential. A submol. moiety, S-dibenzocyclooctadiene (DBCOD) that is composed of a flexible eight-membered ring connecting to a Ph ring at each end, undergoes a conformational change from twist-boat to chair under a low-energy stimulus such as near IR irradiation, resulting in thermal contraction of DBCOD-based polymer. Exptl. evidence corroborated by theor. calculations indicates that introducing mol. asymmetry can reduce crystallinity significantly and consequently facilitate the kinetics of the conformational change. It has been demonstrated that the neg. thermal expansion (NTE) coefficient of a DBCOD-based polymer system can be adjusted in a range from -1140 to -2350 ppm K^-1. -2350 ppm K^-1 is ≈10 times better than the value reported by the second best NTE system. And 3-(4-Aminophenoxy)aniline (cas: 2657-87-6) was used in the research process.

3-(4-Aminophenoxy)aniline is one of ethers-buliding-blocks. Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. Application In Synthesis of 3-(4-Aminophenoxy)anilineEthers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Schmidt, Matthias;Ungvari, Johannes;Gloede, Julia;Dobner, Bodo;Langner, Andreas published 《New 1,3-dioxolane and 1,3-dioxane derivatives as effective modulators to overcome multidrug resistance》 in 2007. The article was appeared in 《Bioorganic & Medicinal Chemistry》. They have made some progress in their research.Formula: C15H16O2 The article mentions the following:

Multidrug resistance (MDR) to antitumor agents represents a major obstacle to a successful chemotherapy of cancer. Overexpression of P-glycoprotein (p-gp) seems to be the major factor responsible for MDR. A large number of chem. unrelated compounds are known to interact with p-gp resulting in a decreasing resistance. In our efforts related to structure-activity studies of new potential MDR reversal agents we synthesized a series of compounds that differ in the aromatic core structure, the linker, and the basic moiety. For our search of new aromatic core structures we synthesized novel 2,2-diphenyl-1,3-dioxolane, 2,2-diphenyl-1,3-dioxane, and 4,5-diphenyl-1,3-dioxolane derivatives A range of lipophilic linker structures and protonable basic moieties were synthesized and investigated to optimize the structure of the potential MDR-modulators. The compounds were tested in vitro using human Caco-2 cells. Both the cytotoxicity of the synthons and their ability to resensitize the cells were determined with a MTT assay. The results show that at low concentration various substances reverse tumor cell MDR. Some of the new structures show better effects than established modulators like trifluoperazine. To complete the study, the researchers used Dimethoxydiphenylmethane (cas: 2235-01-0) .

The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.Formula: C15H16O2

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Recommanded Product: 2097273-59-9In 2020, Liu, Yanhong;Yang, Yiying;Zhu, Rongxiu;Zhang, Dongju published 《Computational Clarification of Synergetic Ru^II/Cu^I-Metallaphotoredox Catalysis in C(sp³)-N Cross-Coupling Reactions of Alkyl Redox-Active Esters with Anilines》. 《ACS Catalysis》published the findings. The article contains the following contents:

The C-N coupling of alkyl electrophiles for amine synthesis is a less-developed area in comparison with that of aryl electrophiles largely because of the difficulty in product-generating C(sp³)-N reductive elimination. The recent work by Hu et al. developed an effective strategy for the C-N coupling of alkyl redox-active esters with anilines by merging photoredox catalysis and copper catalysis with an oxoacetic acid ligand (LH₂). Here, we present a DFT-based computational study to understand how the special dual catalysis works in a cooperative fashion with the assistance of the ligand. Photoredox catalysis is found to occur most possibly through an oxidative quenching mechanism (Ru^II/*Ru^II/Ru^III/Ru^II) with Et₃N as the quencher rather than with the exptl. proposed copper complex. Copper catalytic cycle (Cu^I/Cu^II/Cu^III/Cu^I) is predicted to proceed via a Cu^I-oxidation-first pathway instead of the hypothetical aniline-deprotonation-first pathway in the experiment, and the most likely catalytic active species is identified as the Cu^ILH complex. With the Ru^II/Cu^I-metallaphotoredox catalysis, the most feasible mechanism for the C(sp³)-N cross-coupling involves six steps: (i) generation of cyclohexyl radical (Cy^•) via the single electron transfer (SET) from photoexcited *Ru^II to the complex of redox-active ester with Cu^I, (ii) coordination of aniline to Cu^I center, (iii) Cy^• radical addition to Cu^I center, (iv) SET between Cu^II-cyclohexyl aniline complex and generated Et₃N^•+, (v) deprotonation of aniline, and (vi) reductive elimination of the Cu^III-cyclohexyl amido intermediate to produce the C(sp³)-N coupling product. The Cu^I complex is identified to play a dual role in the title reaction, which acts as the promoter in oxidative quenching process and as the catalyst in the copper catalytic cycle. To complete the study, the researchers used 2,6-Dimethoxyanilino(oxo)acetic acid (cas: 2097273-59-9) .

2,6-Dimethoxyanilino(oxo)acetic acid is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Recommanded Product: 2097273-59-9 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ranu, Brindaban C.;Jana, Ranjan;Samanta, Sampak published 《A simple, efficient and general procedure for acetalization of carbonyl compounds and deprotection of acetals under the catalysis of indium(III) chloride》 in 2004. The article was appeared in 《Advanced Synthesis & Catalysis》. They have made some progress in their research.Related Products of 2235-01-0 The article mentions the following:

Indium(III) chloride efficiently catalyzed the protection of a variety of aldehydes and ketones to their corresponding 1,3-dioxolanes and dialkyl acetals in refluxing cyclohexane. However, deprotection of acetals was also achieved in refluxing aqueous MeOH under the catalysis of In(III) chloride. And Dimethoxydiphenylmethane (cas: 2235-01-0) was used in the research process.

Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Related Products of 2235-01-0 The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Braslau, Rebecca;Burrill, Leland C. II;Chaplinski, Vladimir;Howden, Rodney;Papa, Patrick W. published 《Studies in the stereoselective trapping of prochiral carbon radicals by optically active camphoxyl nitroxides》 in 1997. The article was appeared in 《Tetrahedron: Asymmetry》. They have made some progress in their research.Computed Properties of C15H16O2 The article mentions the following:

Optically active camphoxyl nitroxides, e.g. I, derived from camphene react with prochiral carbon radicals to give diastereomeric coupling products, e.g. II. The diastereomeric ratio can be conveniently measured by ¹H-NMR spectroscopy, in contrast to previous work employing steroidal nitroxides. The structure of the camphoxyl radical was modified and all couplings resulted in modest diastereoselectivity.Dimethoxydiphenylmethane (cas: 2235-01-0) were involved in the experimental procedure.

The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom.Computed Properties of C15H16O2

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Quality Control of Dimethoxydiphenylmethane《Torquoselective 6π-Electron Electrocyclic Ring Closure of 1-Azatrienes Containing Acyclic Chirality at the C-Terminus》 was published in 2006. The authors were Sydorenko, Nadiya;Hsung, Richard P.;Vera, Eymi L., and the article was included in《Organic Letters》. The author mentioned the following in the article:

Torquoselective pericyclic ring closures of 1-azatrienes that contain acyclic chirality at the C-terminus are described herein. To complete the study, the researchers used Dimethoxydiphenylmethane (cas: 2235-01-0) .

For example, the most common synthesis of ethers involves the attack of an alkoxide ion on an alkyl halide. This method is called Williamson ether synthesis.Quality Control of Dimethoxydiphenylmethane

Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem