Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 530-59-6, formula is C11H12O5, Name is 3,5-Dimethoxy-4-hydroxycinnamic acid. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Related Products of 530-59-6.
Jalloul, Amel ben;Chaar, Hatem;Tounsi, Moufida Saidani;Abderrabba, Manef research published 《 Variations in phenolic composition and antioxidant activities of Scabiosa maritima (Scabiosa atropurpurea sub. maritima L.) crude extracts and fractions according to growth stage and plant part》, the research content is summarized as follows. This study aimed to assess for the first time how growing stage and plant part affect the phytochem. contents and antioxidant capacities of extracts and fractions of Scabiosa Atropurpurea sub. Maritima L. (S.maritima). An experiment was conducted on the different parts (leaves, stem, roots, inflorescences, and fruits) of plants collected from the Zaghouan region, Tunisia, at different growing stages: vegetative stage (March), early budding stage (Apr.), late flowering stage (May) and late maturing stage (June). The various plant parts were subjected to hydro-methanolic extraction and sequential solvent fractionation (Chloroform and Acetate). For each extract or fraction, content of total phenolics (TPC), flavonol, tannin (CTC) and total flavonoids (TFC) were quantified. The antioxidant activity of different extracts was assessed using total antioxidant capacity (TAC), ferric reducing power (FRAP), 1, 1-diphenyl-2-picryl hydrazyl (DPPH) and 3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging activities. A Multiple Factor Anal. (MFA) and hierarchical clustering were done on the data set obtained from the various measurements. Addnl., the chem. composition of five selected crude extracts was determined by high performance liquid chromatog. coupled with a diode array (HPLC-DAD). Phytochem. compounds (phenolic, flavonoids, flavonol and tannin) and antioxidant activities (TAC, FRAP, ABTS and DPPH) of S.maritima extracts and fractions differ among plant parts and change throughout the growing stages. The highest phytochem. content and antioxidant activities of plant parts during the different growing stages were mainly recorded in acetate fractions. Leaves generally exhibited higher phytochem. content and antioxidant activity compared to other plant parts. Their highest values were reached during flowering season (plants collected in May). Unlike leaves and stem, roots exhibited their highest phytochem. content and antioxidant activity in June. The MFA results distinguished leaf samples from the other plant parts and highlighted a strong correlation between phytochem. content and antioxidant capacity. High levels of catechin hydrate (ranging from 1951.86 to 6748.97 mg/100 g of extract) were recorded in all samples. Leaf samples were found to contain high amounts of luteolin-7-O glucoside and kaempferol-3-O-rutinoside while particularly high contents of resorcinol and catechol (226.00 and 57.71 mg/100 g of extract, resp.) were observed in the stem sample.
530-59-6, Sinapinic acid is a chemical compound that is the dihydroxybenzoic acid derivative of sinapic acid. It has been shown to have anti-inflammatory properties in vitro and in vivo. Sinapinic acid inhibits the activity of various enzymes, such as cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase-activating protein (FLAP). It also decreases levels of adhesion molecules and downregulates inflammatory response genes. Sinapinic acid has been shown to reduce inflammation by inhibiting the formation of proinflammatory mediators, such as prostaglandin E2 or leukotriene B4, in endothelial cells and mammary epithelial cells.
Sinapic acid is a phenylpropanoid hydroxycinnamic acid with diverse biological activities. Sinapic acid inhibits collagen-induced human platelet aggregation by up to 70% in vitro (IC50 = 1.03 mM). It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) free radicals with IC50 values of 8.3 and 5.4 μg/ml, respectively. Sinapic acid (200 μM) reduces colony formation of SW480 human colon carcinoma cells by 4-fold. It also inhibits colony formation of E. coli, S. enteritidis, and S. aureus on agar (MICs = 2.2, 2, and 1.8 mM, respectively). In vivo, sinapic acid (4 mg/kg, p.o.) increases the time spent in the open arms of the elevated plus maze by approximately 15% in mice, an effect that can be blocked by the GABAA receptor antagonists flumazenil and bicuculline. Sinapic acid is also commonly used as a matrix in protein mass spectrometry.
Sinapic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
cis-Sinapic acid, also known as cis-sinapate or synapitic acid, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. cis-Sinapic acid is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, cis-sinapic acid is primarily located in the cytoplasm. Outside of the human body, cis-sinapic acid can be found in common pea and pulses. This makes cis-sinapic acid a potential biomarker for the consumption of these food products.
Cis-sinapic acid is a 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid in which the double bond has cis-configuration. It has been isolated from the shoots of alfalfa. It has a role as a plant metabolite., Related Products of 530-59-6
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem