Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 111-90-0, formula is C6H14O3, Name is Diethylene Glycol Monoethyl Ether. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Safety of Diethylene Glycol Monoethyl Ether.
Ha, Eun-Sol;Park, Heejun;Lee, Seon-Kwang;Jeong, Ji-Su;Kim, Jeong-Soo;Kim, Min-Soo research published 《 Solubility, solvent effect, and modelling of oxcarbazepine in mono-solvents and N-methyl-2-pyrrolidone + water solvent mixtures at different temperatures and its application for the preparation of nanosuspensions》, the research content is summarized as follows. A solid-liquid equilibrium technique was used to measure the solubility of oxcarbazepine in a mono-solvent and a solvent mixture in the temperature range of 288.15-308.15 K under atm. pressure. Oxcarbazepine in N-methyl-2-pyrrolidone (NMP) showed the highest solubility The KAT-LSER model was applied to determine solvent effect on the solubility of oxcarbazepine in mono-solvents at 298.15 K; the dipolarity-polarizability and cohesive energy d., as the Hildebrand solubility parameter, of the solvent had a greater effect on oxcarbazepine solubility than other parameters. The solubility results of oxcarbazepine in the mono-solvents and mixed (NMP + water) solvents were correlated by applying various models. The oxcarbazepine dissolution in the mono-solvents and mixed (NMP + water) solvents was endothermic and spontaneous. Oxcarbazepine nanosuspensions were prepared based on these solubility results of oxcarbazepine in a mono-solvent and mixed (NMP + water) solvent; the average particle size of all oxcarbazepine nanosuspensions was smaller than 200 nm. The exptl. and calculated solubility results of oxcarbazepine may be utilized in drug development through the application of solubilization techniques to increase the bioavailability of poorly water-soluble drugs.
111-90-0, Diethylene glycol monoethyl ether appears as a colorless, slightly viscous liquid with a mild pleasant odor. Flash point near 190°F. Used to make soaps, dyes, and other chemicals.
Diethylene glycol monoethyl ether is a primary alcohol that is ethanol substituted by a 2-ethoxyethoxy group at position 2. It has a role as a protic solvent. It is a diether, a primary alcohol and a hydroxypolyether. It derives from a diethylene glycol., Safety of Diethylene Glycol Monoethyl Ether
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem