Ethers can again be classified into two varieties: if the alkyl or aryl groups are the same on both sides of the oxygen atom, 530-59-6, formula is C11H12O5, Name is 3,5-Dimethoxy-4-hydroxycinnamic acid. Then it is a simple or symmetrical ether, whereas if they are different, the ethers are called mixed or unsymmetrical ethers. Product Details of C11H12O5.
Guzman-Lorite, M.;Marina, M. L.;Garcia, M. C. research published 《 Pressurized liquids vs. high intensity focused ultrasounds for the extraction of proteins from a pomegranate seed waste》, the research content is summarized as follows. Pomegranate processing results in a waste with high protein content and potential industrial applicability. The reuse of these proteins requires their previous extraction and characterization. Nevertheless, extraction of proteins from vegetal tissues is a difficult task, and methodologies commonly applied for this purpose are non-sustainable and show low yields. Pressurized liquids extraction (PLE) is a sustainable technique scarcely applied for the extraction of proteins. PLE and high intensity focused ultrasounds (HIFU) have been compared in this work to recover proteins from a pomegranate seed waste. PLE extracted more proteins than HIFU, but it took longer and still co-extracted phenolic compounds Extracted proteins were also characterized. Proteins separation by isoelectrofocusing electrophoresis revealed that the extraction technique, PLE or HIFU, significantly affected the solubility of proteins. Peptides released by simulated gastrointestinal digestion of extracted proteins also showed important differences when they were identified by UHPLC-MS/MS. Many identified peptides showed common features with antioxidant, antihypertensive, and hypocholesterolemic peptides. These activities were also confirmed by in vitro studies. PLE samples demonstrated, in general, higher bioactivity than HIFU. In addition to phenolic compounds, significantly co-extracted with proteins by PLE, other interesting compounds were also identified (e.g. azelaic acid). Extraction of proteins is usually carried out using non-sustainable methods that results in low yields and protein degradation This work purposes the use of pressurized liquids extraction (PLE) for the recovery of proteins from a pomegranate seed waste, and compares these results with the obtained using high intensity focused ultrasounds (HIFU). PLE extracted more proteins but it required longer times than HIFU and co-extracted more phenolic compounds The extraction procedure significantly affected proteins solubility and extracts composition Proteins, peptides, and phenolic compounds contributed to the bioactivity of extracts This work demonstrates that this waste is a sustainable and cheap source of proteins and bioactive mols. with high potential for the preparation of bioactive compounds, nutraceuticals, and cosmetics.
530-59-6, Sinapinic acid is a chemical compound that is the dihydroxybenzoic acid derivative of sinapic acid. It has been shown to have anti-inflammatory properties in vitro and in vivo. Sinapinic acid inhibits the activity of various enzymes, such as cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase-activating protein (FLAP). It also decreases levels of adhesion molecules and downregulates inflammatory response genes. Sinapinic acid has been shown to reduce inflammation by inhibiting the formation of proinflammatory mediators, such as prostaglandin E2 or leukotriene B4, in endothelial cells and mammary epithelial cells.
Sinapic acid is a phenylpropanoid hydroxycinnamic acid with diverse biological activities. Sinapic acid inhibits collagen-induced human platelet aggregation by up to 70% in vitro (IC50 = 1.03 mM). It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) free radicals with IC50 values of 8.3 and 5.4 μg/ml, respectively. Sinapic acid (200 μM) reduces colony formation of SW480 human colon carcinoma cells by 4-fold. It also inhibits colony formation of E. coli, S. enteritidis, and S. aureus on agar (MICs = 2.2, 2, and 1.8 mM, respectively). In vivo, sinapic acid (4 mg/kg, p.o.) increases the time spent in the open arms of the elevated plus maze by approximately 15% in mice, an effect that can be blocked by the GABAA receptor antagonists flumazenil and bicuculline. Sinapic acid is also commonly used as a matrix in protein mass spectrometry.
Sinapic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
cis-Sinapic acid, also known as cis-sinapate or synapitic acid, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. cis-Sinapic acid is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, cis-sinapic acid is primarily located in the cytoplasm. Outside of the human body, cis-sinapic acid can be found in common pea and pulses. This makes cis-sinapic acid a potential biomarker for the consumption of these food products.
Cis-sinapic acid is a 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid in which the double bond has cis-configuration. It has been isolated from the shoots of alfalfa. It has a role as a plant metabolite., Product Details of C11H12O5
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem