Jiang, Yan;Yin, Hong-liang;Wang, Li-li;Sun, Xiao-qiang published 《Synthesis of heterocyclic ethers chiral ligands》 in 2014. The article was appeared in 《Huaxue Shiji》. They have made some progress in their research.Application In Synthesis of Dimethoxydiphenylmethane The article mentions the following:
Using L-tartaric acid and benzophenone as reactants, a family of heterocyclic ether chiral ligands ((4S,5S)-2,2-diphenyl-5-((pyridin-2-ylmethoxy) methyl)-1,3-dioxolane-4-yl) methanol I and 2,2′-((((4S, 5S)-2,2-dip-henyl-1,3-dioxolane-4,5-diyl) bis (methylene)) bis (oxy) bis (methylene)) dipyridine II were synthesized via esterification, ketal and reduction reactions. There were two methene groups between the chiralcenter and the ligand atoms, this increased the flexible of chiral ligands, and the catalytic performance was primarily discussed. The experimental procedure involved many compounds, such as Dimethoxydiphenylmethane (cas: 2235-01-0) .
Dimethoxydiphenylmethane is one of ethers-buliding-blocks. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. Application In Synthesis of Dimethoxydiphenylmethane The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.
Reference:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem