Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 530-59-6, formula is C11H12O5, Name is 3,5-Dimethoxy-4-hydroxycinnamic acid. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Category: ethers-buliding-blocks.
da Silva, Elias Alves;Mendes, Thais Demarchi;Pacheco, Thalyta Fraga;Campanha, Raquel Bombarda;Wischral, Daiana;Mendonca, Simone;Camassola, Marli;de Siqueira, Felix Goncalves;Souza, Manoel Teixeira Junior research published 《 Colonization of oil palm empty fruit bunches by basidiomycetes from the Brazilian cerrado: deconstruction of biomass》, the research content is summarized as follows. This study aimed to establish a deconstruction process of oil palm empty fruit bunches (EFBs), employing hydrothermal and biol. pretreatments. Initially, the yields of cellulose, hemicellulose, lignin, extractives and ashes resulting from the autohydrolysis of raw EFBs were measured. The biol. pretreatment of the raw EFBs followed using eight basidiomycetes strains. Finally, an enzymic hydrolysis comparison between basidiomycetes and com. enzymes evaluated glucose and xylose yields, the synergism degree and the reduction of phenolic substances. Autohydrolysis pretreatment presented the best sugar yields after hydrolysis. However, biol. pretreatment provides enzymes and other advantages. The combination of enzymic extracts of basidiomycetes with Celluclast and Novozyme-188 Sigma gave the best glucose yield with Flavodon flavus BRM-055676 (14.78%). Synergism degree analyses showed an increase of 47% in glucose release by the cocktail of Fomes fasciatus BRM-055675 with com. enzymes. The deconstruction of EFBs by biol. pretreatment presented a 2.96 ratio loss of lignin/loss of cellulose with F. flavus BRM-055676. Finally, combinations of enzymic extracts from basidiomycetes and ascomycetes, mainly F. fasciatus BRM-055675, provided the reduction of phenolic substances. 2022 Society of Chem. Industry and John Wiley & Sons, Ltd.
Category: ethers-buliding-blocks, Sinapinic acid is a chemical compound that is the dihydroxybenzoic acid derivative of sinapic acid. It has been shown to have anti-inflammatory properties in vitro and in vivo. Sinapinic acid inhibits the activity of various enzymes, such as cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase-activating protein (FLAP). It also decreases levels of adhesion molecules and downregulates inflammatory response genes. Sinapinic acid has been shown to reduce inflammation by inhibiting the formation of proinflammatory mediators, such as prostaglandin E2 or leukotriene B4, in endothelial cells and mammary epithelial cells.
Sinapic acid is a phenylpropanoid hydroxycinnamic acid with diverse biological activities. Sinapic acid inhibits collagen-induced human platelet aggregation by up to 70% in vitro (IC50 = 1.03 mM). It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) free radicals with IC50 values of 8.3 and 5.4 μg/ml, respectively. Sinapic acid (200 μM) reduces colony formation of SW480 human colon carcinoma cells by 4-fold. It also inhibits colony formation of E. coli, S. enteritidis, and S. aureus on agar (MICs = 2.2, 2, and 1.8 mM, respectively). In vivo, sinapic acid (4 mg/kg, p.o.) increases the time spent in the open arms of the elevated plus maze by approximately 15% in mice, an effect that can be blocked by the GABAA receptor antagonists flumazenil and bicuculline. Sinapic acid is also commonly used as a matrix in protein mass spectrometry.
Sinapic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
cis-Sinapic acid, also known as cis-sinapate or synapitic acid, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. cis-Sinapic acid is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, cis-sinapic acid is primarily located in the cytoplasm. Outside of the human body, cis-sinapic acid can be found in common pea and pulses. This makes cis-sinapic acid a potential biomarker for the consumption of these food products.
Cis-sinapic acid is a 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid in which the double bond has cis-configuration. It has been isolated from the shoots of alfalfa. It has a role as a plant metabolite., 530-59-6.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem