Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. 38256-93-8, formula is C4H11NO, Name is 2-Methoxy-N-methylethanamine. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3. Formula: C4H11NO.
Beaulieu, Pierre L.;Coulombe, Rene;Gillard, James;Brochu, Christian;Duan, Jianmin;Garneau, Michel;Jolicoeur, Eric;Kuhn, Peter;Poupart, Marc-Andre;Rancourt, Jean;Stammers, Timothy A.;Thavonekham, Bounkham;Kukolj, George research published 《 Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase – acylsulfonamides and acylsulfamides as carboxylic acid replacements》, the research content is summarized as follows. Acylsulfonamide and acylsulfamide as surrogates for the carboxylic acid function of N-acetamide-indole-6-carboxylic acids were evaluated as allosteric inhibitors of hepatitis C virus (HCV) NS5B polymerase. Several analogs, e.g., I, displayed excellent antiviral potency against HCV genotypes in cell-based subgenomic replicon assays. Structure-activity relationships are discussed in the context of the crystal structure of an inhibitor NS5B polymerase complex. Absorption, distribution, metabolism, and excretion pharmacokinetic properties of this class of inhibitors are also described.
38256-93-8, 2-Methoxy-N-methylethanamine is a useful research compound. Its molecular formula is C4H11NO and its molecular weight is 89.14 g/mol. The purity is usually 95%.
2-Methoxy-N-methylethanamine is a drug that binds to the cannabinoid receptor CB1. It has been shown to be effective in the treatment of cardiac arrhythmia and may also be used as an anti-inflammatory drug. 2MEMEA has been shown to have pharmacokinetic properties that are different from those of other amines, which may be due to its ability to form hydrogen bonds with water molecules. 2MEMEA also has diversified effects on some types of cancer cells, including hyperproliferative and amine-dependent cancers., Formula: C4H11NO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem